MIABIS on FHIR Implementation Guide - Local Development build (v1.3.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

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Resource Profile: Collection

Collection represents a set of samples and/or data items collected and/or derived in a common context and stored under a common stewardship and available for future research

Usages:

• Examples for this Profile: CollectionName

You can also check for usages in the FHIR IG Statistics

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group	C	0..*	Group	Group of multiple entities Constraints: grp-1
Group.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.extension		0..0		Extension Slice: Unordered, Open by value:url
Group.Slices for extension.extension:MemberEntity.url		1..1	uri	"https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension"
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.modifierExtension	?! This element is a modifier element.	0..*	Extension	Extensions that cannot be ignored
Group.identifier	S This element must be supported. Σ This element is included in summaries.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported. Σ This element is included in summaries.	0..1	boolean	The state of the collection functions.
Group.type	Σ This element is included in summaries.	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
Group.actual	Σ This element is included in summaries. C	1..1	boolean	Descriptive or actual
Group.name	S This element must be supported. Σ This element is included in summaries.	1..1	string	Name of the collection (preferably in English).
Group.managingEntity	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:All Slices				Content/Rules for all slices
Group.Slices for characteristic.characteristic:All Slices.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:All Slices.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x]		1..1		Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x].valueCodeableConcept			CodeableConcept
Group.Slices for characteristic.characteristic:All Slices.value[x].valueBoolean			boolean
Group.Slices for characteristic.characteristic:All Slices.value[x].valueQuantity			Quantity
Group.Slices for characteristic.characteristic:All Slices.value[x].valueRange			Range
Group.Slices for characteristic.characteristic:All Slices.value[x].valueReference			Reference(Any)
Group.Slices for characteristic.characteristic:All Slices.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:ageRange.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:ageRange.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:ageRange.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:sex.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:sex.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:sex.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:storageTemperature.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:storageTemperature.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:materialType.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:materialType.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:materialType.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:diagnosis.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:diagnosis.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Group.Slices for characteristic.characteristic:diagnosis.exclude		1..1	boolean	Group includes or excludes
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Group.type	Base	required	GroupType	📍4.0.1	FHIR Std.
Group.characteristic.​code	Base	example		Not State	Unknown
Group.characteristic.​value[x]	Base	example		Not State	Unknown
Group.characteristic:ageRange.​code	Base	example		Not State	Unknown
Group.characteristic:ageRange.​value[x]	Base	example		Not State	Unknown
Group.characteristic:sex.​code	Base	example		Not State	Unknown
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​code	Base	example		Not State	Unknown
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​code	Base	example		Not State	Unknown
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​code	Base	example		Not State	Unknown
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual"	member.empty() or (actual = true)

This structure is derived from Group

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group		0..*	Group	Group of multiple entities
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.identifier	S This element must be supported.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported.	0..1	boolean	The state of the collection functions.
Group.type		1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Required Pattern: person
Group.name	S This element must be supported.	1..1	string	Name of the collection (preferably in English).
Group.managingEntity	S This element must be supported.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group	C	0..*	Group	Group of multiple entities Constraints: grp-1
Group.id	Σ This element is included in summaries.	0..1	id	Logical id of this artifact
Group.meta	Σ This element is included in summaries.	0..1	Meta	Metadata about the resource
Group.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
Group.language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
Group.text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
Group.contained		0..*	Resource	Contained, inline Resources
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.id		0..1	string	Unique id for inter-element referencing
Group.Slices for extension.extension:MemberEntity.extension		0..0		Extension Slice: Unordered, Open by value:url
Group.Slices for extension.extension:MemberEntity.url		1..1	uri	"https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension"
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.modifierExtension	?! This element is a modifier element.	0..*	Extension	Extensions that cannot be ignored
Group.identifier	S This element must be supported. Σ This element is included in summaries.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported. Σ This element is included in summaries.	0..1	boolean	The state of the collection functions.
Group.type	Σ This element is included in summaries.	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
Group.actual	Σ This element is included in summaries. C	1..1	boolean	Descriptive or actual
Group.code	Σ This element is included in summaries.	0..1	CodeableConcept	Kind of Group members Binding Description: (example): Kind of particular resource; e.g. cow, syringe, lake, etc.
Group.name	S This element must be supported. Σ This element is included in summaries.	1..1	string	Name of the collection (preferably in English).
Group.quantity	Σ This element is included in summaries.	0..1	unsignedInt	Number of members
Group.managingEntity	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:All Slices				Content/Rules for all slices
Group.Slices for characteristic.characteristic:All Slices.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:All Slices.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:All Slices.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:All Slices.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x]		1..1		Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x].valueCodeableConcept			CodeableConcept
Group.Slices for characteristic.characteristic:All Slices.value[x].valueBoolean			boolean
Group.Slices for characteristic.characteristic:All Slices.value[x].valueQuantity			Quantity
Group.Slices for characteristic.characteristic:All Slices.value[x].valueRange			Range
Group.Slices for characteristic.characteristic:All Slices.value[x].valueReference			Reference(Any)
Group.Slices for characteristic.characteristic:All Slices.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:All Slices.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:ageRange.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:ageRange.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:ageRange.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:ageRange.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:sex.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:sex.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:sex.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:sex.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:storageTemperature.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:storageTemperature.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:storageTemperature.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:materialType.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:materialType.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:materialType.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:materialType.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:diagnosis.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:diagnosis.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Group.Slices for characteristic.characteristic:diagnosis.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:diagnosis.period		0..1	Period	Period over which characteristic is tested
Group.member	C	0..*	BackboneElement	Who or what is in group
Group.member.id		0..1	string	Unique id for inter-element referencing
Group.member.extension		0..*	Extension	Additional content defined by implementations
Group.member.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.member.entity		1..1	Reference(Patient | Practitioner | PractitionerRole | Device | Medication | Substance | Group)	Reference to the group member
Group.member.period		0..1	Period	Period member belonged to the group
Group.member.inactive		0..1	boolean	If member is no longer in group
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Group.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Group.type	Base	required	GroupType	📍4.0.1	FHIR Std.
Group.code	Base	example		Not State	Unknown
Group.characteristic.​code	Base	example		Not State	Unknown
Group.characteristic.​value[x]	Base	example		Not State	Unknown
Group.characteristic:ageRange.​code	Base	example		Not State	Unknown
Group.characteristic:ageRange.​value[x]	Base	example		Not State	Unknown
Group.characteristic:sex.​code	Base	example		Not State	Unknown
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​code	Base	example		Not State	Unknown
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​code	Base	example		Not State	Unknown
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​code	Base	example		Not State	Unknown
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual"	member.empty() or (actual = true)

This structure is derived from Group

Summary

Mandatory: 5 elements
Must-Support: 12 elements

Structures

This structure refers to these other structures:

• Collection Organization (https://fhir.bbmri-eric.eu/StructureDefinition/miabis-collection-organization)

Extensions

This structure refers to these extensions:

• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Group.characteristic

Key Elements View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group	C	0..*	Group	Group of multiple entities Constraints: grp-1
Group.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.extension		0..0		Extension Slice: Unordered, Open by value:url
Group.Slices for extension.extension:MemberEntity.url		1..1	uri	"https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension"
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.modifierExtension	?! This element is a modifier element.	0..*	Extension	Extensions that cannot be ignored
Group.identifier	S This element must be supported. Σ This element is included in summaries.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported. Σ This element is included in summaries.	0..1	boolean	The state of the collection functions.
Group.type	Σ This element is included in summaries.	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
Group.actual	Σ This element is included in summaries. C	1..1	boolean	Descriptive or actual
Group.name	S This element must be supported. Σ This element is included in summaries.	1..1	string	Name of the collection (preferably in English).
Group.managingEntity	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:All Slices				Content/Rules for all slices
Group.Slices for characteristic.characteristic:All Slices.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:All Slices.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x]		1..1		Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x].valueCodeableConcept			CodeableConcept
Group.Slices for characteristic.characteristic:All Slices.value[x].valueBoolean			boolean
Group.Slices for characteristic.characteristic:All Slices.value[x].valueQuantity			Quantity
Group.Slices for characteristic.characteristic:All Slices.value[x].valueRange			Range
Group.Slices for characteristic.characteristic:All Slices.value[x].valueReference			Reference(Any)
Group.Slices for characteristic.characteristic:All Slices.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:ageRange.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:ageRange.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:ageRange.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:sex.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:sex.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:sex.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:storageTemperature.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:storageTemperature.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:materialType.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:materialType.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:materialType.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:diagnosis.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:diagnosis.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Group.Slices for characteristic.characteristic:diagnosis.exclude		1..1	boolean	Group includes or excludes
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Group.type	Base	required	GroupType	📍4.0.1	FHIR Std.
Group.characteristic.​code	Base	example		Not State	Unknown
Group.characteristic.​value[x]	Base	example		Not State	Unknown
Group.characteristic:ageRange.​code	Base	example		Not State	Unknown
Group.characteristic:ageRange.​value[x]	Base	example		Not State	Unknown
Group.characteristic:sex.​code	Base	example		Not State	Unknown
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​code	Base	example		Not State	Unknown
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​code	Base	example		Not State	Unknown
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​code	Base	example		Not State	Unknown
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual"	member.empty() or (actual = true)

Differential View

This structure is derived from Group

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group		0..*	Group	Group of multiple entities
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.identifier	S This element must be supported.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported.	0..1	boolean	The state of the collection functions.
Group.type		1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Required Pattern: person
Group.name	S This element must be supported.	1..1	string	Name of the collection (preferably in English).
Group.managingEntity	S This element must be supported.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Status	Usage	ValueSet	Version	Source
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Snapshot View

Name	Flags	Card.	Type	Description & Constraints    Filter: Bindings Constraints Obligations
Group	C	0..*	Group	Group of multiple entities Constraints: grp-1
Group.id	Σ This element is included in summaries.	0..1	id	Logical id of this artifact
Group.meta	Σ This element is included in summaries.	0..1	Meta	Metadata about the resource
Group.implicitRules	?! This element is a modifier element. Σ This element is included in summaries.	0..1	uri	A set of rules under which this content was created
Group.language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
Group.text		0..1	Narrative	Text summary of the resource, for human interpretation This profile does not constrain the narrative in regard to content, language, or traceability to data elements
Group.contained		0..*	Resource	Contained, inline Resources
Group.Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for extension.extension:numberOfSubjects	S This element must be supported.	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
Group.Slices for extension.extension:inclusionCriteria	S This element must be supported.	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
Group.Slices for extension.extension:MemberEntity	S This element must be supported.	0..*	(Complex)	Member Entity URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension
Group.Slices for extension.extension:MemberEntity.id		0..1	string	Unique id for inter-element referencing
Group.Slices for extension.extension:MemberEntity.extension		0..0		Extension Slice: Unordered, Open by value:url
Group.Slices for extension.extension:MemberEntity.url		1..1	uri	"https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension"
Group.Slices for extension.extension:MemberEntity.value[x]		0..1	Reference(Specimen)	Value of extension
Group.modifierExtension	?! This element is a modifier element.	0..*	Extension	Extensions that cannot be ignored
Group.identifier	S This element must be supported. Σ This element is included in summaries.	1..1	Identifier	ID of the collection.
Group.active	S This element must be supported. Σ This element is included in summaries.	0..1	boolean	The state of the collection functions.
Group.type	Σ This element is included in summaries.	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
Group.actual	Σ This element is included in summaries. C	1..1	boolean	Descriptive or actual
Group.code	Σ This element is included in summaries.	0..1	CodeableConcept	Kind of Group members Binding Description: (example): Kind of particular resource; e.g. cow, syringe, lake, etc.
Group.name	S This element must be supported. Σ This element is included in summaries.	1..1	string	Name of the collection (preferably in English).
Group.quantity	Σ This element is included in summaries.	0..1	unsignedInt	Number of members
Group.managingEntity	S This element must be supported. Σ This element is included in summaries.	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Group.Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code Slicing Note: The rules on this element (including its children) apply to all the slices, but are not repeated in them
Group.Slices for characteristic.characteristic:All Slices				Content/Rules for all slices
Group.Slices for characteristic.characteristic:All Slices.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:All Slices.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:All Slices.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:All Slices.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x]		1..1		Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:All Slices.value[x].valueCodeableConcept			CodeableConcept
Group.Slices for characteristic.characteristic:All Slices.value[x].valueBoolean			boolean
Group.Slices for characteristic.characteristic:All Slices.value[x].valueQuantity			Quantity
Group.Slices for characteristic.characteristic:All Slices.value[x].valueRange			Range
Group.Slices for characteristic.characteristic:All Slices.value[x].valueReference			Reference(Any)
Group.Slices for characteristic.characteristic:All Slices.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:All Slices.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:ageRange	S This element must be supported.	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
Group.Slices for characteristic.characteristic:ageRange.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:ageRange.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:ageRange.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:ageRange.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:ageRange.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:ageRange.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:ageRange.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:ageRange.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
Group.Slices for characteristic.characteristic:ageRange.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:ageRange.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:ageRange.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:ageRange.value[x]		1..1	Range	Value held by characteristic Binding Description: (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
Group.Slices for characteristic.characteristic:ageRange.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:ageRange.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:sex	S This element must be supported.	1..*	BackboneElement	The sex of the individuals in the collection.
Group.Slices for characteristic.characteristic:sex.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:sex.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:sex.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:sex.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:sex.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:sex.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:sex.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:sex.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
Group.Slices for characteristic.characteristic:sex.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:sex.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:sex.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:sex.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
Group.Slices for characteristic.characteristic:sex.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:sex.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:storageTemperature	S This element must be supported.	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
Group.Slices for characteristic.characteristic:storageTemperature.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:storageTemperature.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:storageTemperature.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:storageTemperature.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:storageTemperature.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:storageTemperature.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
Group.Slices for characteristic.characteristic:storageTemperature.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:storageTemperature.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:materialType	S This element must be supported.	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
Group.Slices for characteristic.characteristic:materialType.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:materialType.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:materialType.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:materialType.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:materialType.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:materialType.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:materialType.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:materialType.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
Group.Slices for characteristic.characteristic:materialType.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:materialType.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:materialType.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:materialType.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
Group.Slices for characteristic.characteristic:materialType.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:materialType.period		0..1	Period	Period over which characteristic is tested
Group.Slices for characteristic.characteristic:diagnosis	S This element must be supported.	0..*	BackboneElement	The diagnosis of the individuals in the collection.
Group.Slices for characteristic.characteristic:diagnosis.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.Slices for characteristic.characteristic:diagnosis.code		1..1	CodeableConcept	Kind of characteristic Binding Description: (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
Group.Slices for characteristic.characteristic:diagnosis.code.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding		1..*	Coding	Code defined by a terminology system Fixed Value: (Complex)
Group.Slices for characteristic.characteristic:diagnosis.code.coding.id		0..1	string	Unique id for inter-element referencing
Group.Slices for characteristic.characteristic:diagnosis.code.coding.extension		0..*	Extension	Additional content defined by implementations
Group.Slices for characteristic.characteristic:diagnosis.code.coding.system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
Group.Slices for characteristic.characteristic:diagnosis.code.coding.version		0..1	string	Version of the system - if relevant
Group.Slices for characteristic.characteristic:diagnosis.code.coding.code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
Group.Slices for characteristic.characteristic:diagnosis.code.coding.display		0..1	string	Representation defined by the system
Group.Slices for characteristic.characteristic:diagnosis.code.coding.userSelected		0..1	boolean	If this coding was chosen directly by the user
Group.Slices for characteristic.characteristic:diagnosis.code.text		0..1	string	Plain text representation of the concept
Group.Slices for characteristic.characteristic:diagnosis.value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Group.Slices for characteristic.characteristic:diagnosis.exclude		1..1	boolean	Group includes or excludes
Group.Slices for characteristic.characteristic:diagnosis.period		0..1	Period	Period over which characteristic is tested
Group.member	C	0..*	BackboneElement	Who or what is in group
Group.member.id		0..1	string	Unique id for inter-element referencing
Group.member.extension		0..*	Extension	Additional content defined by implementations
Group.member.modifierExtension	?! This element is a modifier element. Σ This element is included in summaries.	0..*	Extension	Extensions that cannot be ignored even if unrecognized
Group.member.entity		1..1	Reference(Patient | Practitioner | PractitionerRole | Device | Medication | Substance | Group)	Reference to the group member
Group.member.period		0..1	Period	Period member belonged to the group
Group.member.inactive		0..1	boolean	If member is no longer in group
Documentation for this format

Terminology Bindings

Path	Status	Usage	ValueSet	Version	Source
Group.language	Base	preferred	Common Languages	📍4.0.1	FHIR Std.
Group.type	Base	required	GroupType	📍4.0.1	FHIR Std.
Group.code	Base	example		Not State	Unknown
Group.characteristic.​code	Base	example		Not State	Unknown
Group.characteristic.​value[x]	Base	example		Not State	Unknown
Group.characteristic:ageRange.​code	Base	example		Not State	Unknown
Group.characteristic:ageRange.​value[x]	Base	example		Not State	Unknown
Group.characteristic:sex.​code	Base	example		Not State	Unknown
Group.characteristic:sex.​value[x]	Base	required	AdministrativeGender	📦4.0.1	FHIR Std.
Group.characteristic:storageTemperature.​code	Base	example		Not State	Unknown
Group.characteristic:storageTemperature.​value[x]	Base	required	Storage Temperature Value Set	📦1.3.0	This IG
Group.characteristic:materialType.​code	Base	example		Not State	Unknown
Group.characteristic:materialType.​value[x]	Base	required	Collection Sample Type Value Set	📦1.3.0	This IG
Group.characteristic:diagnosis.​code	Base	example		Not State	Unknown
Group.characteristic:diagnosis.​value[x]	Base	required	DiagnosisVS	📦1.3.0	This IG

Constraints

Id	Grade	Path(s)	Description	Expression
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources	contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource	contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated	contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label	contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management	text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children	hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both	extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual"	member.empty() or (actual = true)

This structure is derived from Group

Summary

Mandatory: 5 elements
Must-Support: 12 elements

Structures

This structure refers to these other structures:

• Collection Organization (https://fhir.bbmri-eric.eu/StructureDefinition/miabis-collection-organization)

Extensions

This structure refers to these extensions:

• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-member-entity-extension

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Group.characteristic