MIABIS on FHIR Implementation Guide - Local Development build (v1.0.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

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Resource Profile: Collection

Collection represents a set of samples and/or data items collected and/or derived in a common context and stored under a common stewardship and available for future research

Usage:

• Examples for this Resource Profile: CollectionName

Formal Views of Profile Content

Description of Profiles, Differentials, Snapshots and how the different presentations work.

• Key Elements Table
• Differential Table
• Snapshot Table
• Statistics/References
• All

Name	Flags	Card.	Type	Description & Constraints
Group	C	0..*	Group	Group of multiple entities dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management grp-1: Can only have members if group is "actual"
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity"
value[x]		1..1	Reference(Specimen)	Value of extension ele-1: All FHIR elements must have a @value or children
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
identifier	SΣ	1..1	Identifier	ID of the collection. ele-1: All FHIR elements must have a @value or children
active	SΣ	0..1	boolean	The state of the collection functions. ele-1: All FHIR elements must have a @value or children
type	Σ	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. ele-1: All FHIR elements must have a @value or children Required Pattern: person
actual	ΣC	1..1	boolean	Descriptive or actual ele-1: All FHIR elements must have a @value or children
name	SΣ	1..1	string	Name of the collection (preferably in English). ele-1: All FHIR elements must have a @value or children
managingEntity	SΣ	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc. ele-1: All FHIR elements must have a @value or children
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code ele-1: All FHIR elements must have a @value or children
characteristic:All Slices				Content/Rules for all slices
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children
value[x]		1..1		Value held by characteristic Binding Description (No ValueSet): (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc. ele-1: All FHIR elements must have a @value or children
valueCodeableConcept			CodeableConcept
valueBoolean			boolean
valueQuantity			Quantity
valueRange			Range
valueReference			Reference(Any)
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
value[x]		1..1	Range	Value held by characteristic ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Group.type	required	Pattern: person http://hl7.org/fhir/ValueSet/group-type|4.0.1 from the FHIR Standard
Group.characteristic.code	example
Group.characteristic.value[x]	example
Group.characteristic:ageRange.code	example	Pattern: Age
Group.characteristic:sex.code	example	Pattern: Sex
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.code	example	Pattern: StorageTemperature
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.code	example	Pattern: MaterialType
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.code	example	Pattern: Diagnosis
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual" : member.empty() or (actual = true)

This structure is derived from Group

Name	Flags	Card.	Type	Description & Constraints
Group		0..*	Group	Group of multiple entities
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity
value[x]		1..1	Reference(Specimen)	Value of extension
identifier	S	1..1	Identifier	ID of the collection.
active	S	0..1	boolean	The state of the collection functions.
type		1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Required Pattern: person
name	S	1..1	string	Name of the collection (preferably in English).
managingEntity	S	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
value[x]		1..1	Range	Value held by characteristic
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Name	Flags	Card.	Type	Description & Constraints
Group	C	0..*	Group	Group of multiple entities grp-1: Can only have members if group is "actual"
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity"
value[x]		1..1	Reference(Specimen)	Value of extension
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	ID of the collection.
active	SΣ	0..1	boolean	The state of the collection functions.
type	Σ	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
actual	ΣC	1..1	boolean	Descriptive or actual
code	Σ	0..1	CodeableConcept	Kind of Group members Binding Description (No ValueSet): (example): Kind of particular resource; e.g. cow, syringe, lake, etc.
name	SΣ	1..1	string	Name of the collection (preferably in English).
quantity	Σ	0..1	unsignedInt	Number of members
managingEntity	SΣ	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code
characteristic:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
value[x]		1..1		Value held by characteristic Binding Description (No ValueSet): (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
valueCodeableConcept			CodeableConcept
valueBoolean			boolean
valueQuantity			Quantity
valueRange			Range
valueReference			Reference(Any)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	Range	Value held by characteristic
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
member	C	0..*	BackboneElement	Who or what is in group
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
entity		1..1	Reference(Patient | Practitioner | PractitionerRole | Device | Medication | Substance | Group)	Reference to the group member
period		0..1	Period	Period member belonged to the group
inactive		0..1	boolean	If member is no longer in group
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Group.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Group.type	required	Pattern: person http://hl7.org/fhir/ValueSet/group-type|4.0.1 from the FHIR Standard
Group.code	example
Group.characteristic.code	example
Group.characteristic.value[x]	example
Group.characteristic:ageRange.code	example	Pattern: Age
Group.characteristic:sex.code	example	Pattern: Sex
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.code	example	Pattern: StorageTemperature
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.code	example	Pattern: MaterialType
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.code	example	Pattern: Diagnosis
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual" : member.empty() or (actual = true)

This structure is derived from Group

Summary

Mandatory: 5 elements
Must-Support: 12 elements

Structures

This structure refers to these other structures:

• Collection Organization (https://fhir.bbmri-eric.eu/StructureDefinition/miabis-collection-organization)

Extensions

This structure refers to these extensions:

• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension
• http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Group.characteristic

Key Elements View

Name	Flags	Card.	Type	Description & Constraints
Group	C	0..*	Group	Group of multiple entities dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management grp-1: Can only have members if group is "actual"
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required) ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity"
value[x]		1..1	Reference(Specimen)	Value of extension ele-1: All FHIR elements must have a @value or children
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
identifier	SΣ	1..1	Identifier	ID of the collection. ele-1: All FHIR elements must have a @value or children
active	SΣ	0..1	boolean	The state of the collection functions. ele-1: All FHIR elements must have a @value or children
type	Σ	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. ele-1: All FHIR elements must have a @value or children Required Pattern: person
actual	ΣC	1..1	boolean	Descriptive or actual ele-1: All FHIR elements must have a @value or children
name	SΣ	1..1	string	Name of the collection (preferably in English). ele-1: All FHIR elements must have a @value or children
managingEntity	SΣ	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc. ele-1: All FHIR elements must have a @value or children
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code ele-1: All FHIR elements must have a @value or children
characteristic:All Slices				Content/Rules for all slices
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children
value[x]		1..1		Value held by characteristic Binding Description (No ValueSet): (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc. ele-1: All FHIR elements must have a @value or children
valueCodeableConcept			CodeableConcept
valueBoolean			boolean
valueQuantity			Quantity
valueRange			Range
valueReference			Reference(Any)
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
value[x]		1..1	Range	Value held by characteristic ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection. ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. ele-1: All FHIR elements must have a @value or children Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required) ele-1: All FHIR elements must have a @value or children
exclude		1..1	boolean	Group includes or excludes ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Group.type	required	Pattern: person http://hl7.org/fhir/ValueSet/group-type|4.0.1 from the FHIR Standard
Group.characteristic.code	example
Group.characteristic.value[x]	example
Group.characteristic:ageRange.code	example	Pattern: Age
Group.characteristic:sex.code	example	Pattern: Sex
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.code	example	Pattern: StorageTemperature
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.code	example	Pattern: MaterialType
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.code	example	Pattern: Diagnosis
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual" : member.empty() or (actual = true)

Differential View

This structure is derived from Group

Name	Flags	Card.	Type	Description & Constraints
Group		0..*	Group	Group of multiple entities
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity
value[x]		1..1	Reference(Specimen)	Value of extension
identifier	S	1..1	Identifier	ID of the collection.
active	S	0..1	boolean	The state of the collection functions.
type		1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Required Pattern: person
name	S	1..1	string	Name of the collection (preferably in English).
managingEntity	S	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
value[x]		1..1	Range	Value held by characteristic
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection.
code		1..1	CodeableConcept	Kind of characteristic Required Pattern: At least the following
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Snapshot View

Name	Flags	Card.	Type	Description & Constraints
Group	C	0..*	Group	Group of multiple entities grp-1: Can only have members if group is "actual"
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
Slices for extension		0..*	Extension	Extension Slice: Unordered, Open by value:url
extension:numberOfSubjects	S	0..1	integer	Total number of subjects included in the collection. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
extension:inclusionCriteria	S	0..*	CodeableConcept	Information on type of parameters that determine which subjects will become collection participants. URL: https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension Binding: Inclusion Criteria ValueSet (required)
extension:MemberEntity	S	0..*	(Complex)	Optional Extensions Element URL: http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity
id		0..1	string	Unique id for inter-element referencing
extension		0..0
url		1..1	uri	"http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity"
value[x]		1..1	Reference(Specimen)	Value of extension
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	SΣ	1..1	Identifier	ID of the collection.
active	SΣ	0..1	boolean	The state of the collection functions.
type	Σ	1..1	code	The type of resources this group contains. For this resource type, this is always set to person. (should be specimen, but this is only supported in R5) Binding: GroupType (required): Types of resources that are part of group. Required Pattern: person
actual	ΣC	1..1	boolean	Descriptive or actual
code	Σ	0..1	CodeableConcept	Kind of Group members Binding Description (No ValueSet): (example): Kind of particular resource; e.g. cow, syringe, lake, etc.
name	SΣ	1..1	string	Name of the collection (preferably in English).
quantity	Σ	0..1	unsignedInt	Number of members
managingEntity	SΣ	1..1	Reference(Collection Organization)	Organization resource containing details of this collection, such as contact information, publications, etc.
Slices for characteristic		2..*	BackboneElement	Include / Exclude group members by Trait Slice: Unordered, Open by value:code
characteristic:All Slices				Content/Rules for all slices
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc.
value[x]		1..1		Value held by characteristic Binding Description (No ValueSet): (example): Value of descriptive member characteristic; e.g. red, male, pneumonia, Caucasian, etc.
valueCodeableConcept			CodeableConcept
valueBoolean			boolean
valueQuantity			Quantity
valueRange			Range
valueReference			Reference(Any)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:ageRange	S	0..1	BackboneElement	Age of youngest and oldest sample donor at the time of sample donation.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Age
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	Range	Value held by characteristic
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:sex	S	1..*	BackboneElement	The sex of the individuals in the collection.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Sex
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: AdministrativeGender (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:storageTemperature	S	0..*	BackboneElement	The long-term storage temperature at which the sample(s) are stored after preparation, based on SPREC v3.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: StorageTemperature
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Storage Temperature Value Set (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:materialType	S	1..*	BackboneElement	The biospecimen saved from a biological entity for propagation e.g. testing, diagnostics, treatment or research purposes.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: MaterialType
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: Collection Sample Type Value Set (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
characteristic:diagnosis	S	0..*	BackboneElement	The diagnosis of the individuals in the collection.
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code		1..1	CodeableConcept	Kind of characteristic Binding Description (No ValueSet): (example): List of characteristics used to describe group members; e.g. gender, age, owner, location, etc. Required Pattern: At least the following
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
coding		1..*	Coding	Code defined by a terminology system Fixed Value: (complex)
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
system		1..1	uri	Identity of the terminology system Fixed Value: https://fhir.bbmri-eric.eu/CodeSystem/miabis-characteristicCS
version		0..1	string	Version of the system - if relevant
code		1..1	code	Symbol in syntax defined by the system Fixed Value: Diagnosis
display		0..1	string	Representation defined by the system
userSelected		0..1	boolean	If this coding was chosen directly by the user
text		0..1	string	Plain text representation of the concept
value[x]		1..1	CodeableConcept	Value held by characteristic Binding: DiagnosisVS (required)
exclude		1..1	boolean	Group includes or excludes
period		0..1	Period	Period over which characteristic is tested
member	C	0..*	BackboneElement	Who or what is in group
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
entity		1..1	Reference(Patient | Practitioner | PractitionerRole | Device | Medication | Substance | Group)	Reference to the group member
period		0..1	Period	Period member belonged to the group
inactive		0..1	boolean	If member is no longer in group
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet / Code	URI
Group.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
Group.type	required	Pattern: person http://hl7.org/fhir/ValueSet/group-type|4.0.1 from the FHIR Standard
Group.code	example
Group.characteristic.code	example
Group.characteristic.value[x]	example
Group.characteristic:ageRange.code	example	Pattern: Age
Group.characteristic:sex.code	example	Pattern: Sex
Group.characteristic:sex.value[x]	required	AdministrativeGender http://hl7.org/fhir/ValueSet/administrative-gender from the FHIR Standard
Group.characteristic:storageTemperature.code	example	Pattern: StorageTemperature
Group.characteristic:storageTemperature.value[x]	required	StorageTemperatureVS (a valid code from MIABIS Storage Temperature Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-storage-temperature-vs from this IG
Group.characteristic:materialType.code	example	Pattern: MaterialType
Group.characteristic:materialType.value[x]	required	CollectionSampleTypeVS (a valid code from MIABIS Collection Sample Type Code System) https://fhir.bbmri-eric.eu/ValueSet/miabis-collection-sample-typ-vs from this IG
Group.characteristic:diagnosis.code	example	Pattern: Diagnosis
Group.characteristic:diagnosis.value[x]	required	DiagnosisVS https://fhir.bbmri-eric.eu/ValueSet/miabis-diagnosis-vs from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	Group	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	Group	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	Group	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	Group	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	Group	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
grp-1	error	Group	Can only have members if group is "actual" : member.empty() or (actual = true)

This structure is derived from Group

Summary

Mandatory: 5 elements
Must-Support: 12 elements

Structures

This structure refers to these other structures:

• Collection Organization (https://fhir.bbmri-eric.eu/StructureDefinition/miabis-collection-organization)

Extensions

This structure refers to these extensions:

• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-number-of-subjects-extension
• https://fhir.bbmri-eric.eu/StructureDefinition/miabis-inclusion-criteria-extension
• http://hl7.org/fhir/5.0/StructureDefinition/extension-Group.member.entity

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of Group.characteristic